Department of Physics and Beckman Institute. Theoretical and computational biophysics group. Glasswork by Luke Jerram.
Mature HIV virus capsid
Viral particles of HIV-1 contain conical cores (or "cones") formed by a protein shell composed of the viral capsid protein (CA). The capsid protein (CA) plays critical roles in both late and early stages of the infection process and is widely viewed as an important unexploited therapeutic target. Capsid protein assembles into hexamers (gold) and pentamers (green), the curvature of the capsid is determined by the location of the pentamers.